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The product explanations of turmeric extract containing curcumin of 350 times absorption factor

Microcell Co. Ltd
SEIRI OSHIRO
Representative Director
Phone Number +81-098-857-2072
Fax Number +81-098-857-2276
E-mail Adders info@ukonyu.co.jp
27-21 kyohara-cho, Naha City, Okinawa, Japan 901-0151

Introduction

We are pleased to provide you, especially beginners, with an explanation of our product, 「BEAUTY UKON/350」(Temporary name)that is turmeric extract containing curcumin of 350 times absorption factor by being dissolved curcumin in cooking oils such as extra virgin olive oil.

The turmeric is a medical herb of the ginger department of an annual plant the first grader that is called UTCHIN, UKON, Curcuma and turmeric as a spice, etc. We use its rhizome usually.It is known well in a Japanese country that the turmeric is a specific medicine of the liver and effective well for the hangover. Also, effective in cancer and Alzheimer is being clarified by recent worldwide research. However, it cannot be said that the pharmacologic effect of the turmeric will be known worldwide.

1.History of turmeric
The turmeric is symbolized in the curry and has been eaten all over the world in history as human race's important food. In India and Asia, it is patronized as one of the important herbs still though the usage is different.

The turmeric is a plant of the ginger department and grows naturally in the provinces to the subtropics Okinawa prefecture in Japan from tropical India and is cultivated. There are about 50 kinds of the kinds. However, only several kinds of are being used as a medicinal use.

Most kinds are Turmeric, Wild turmeric, Zedoary、Medicinal turmeric and Black turmeric, and other such turmeric.

All the above-mentioned turmeric is cultivated and the examination cultivation is advanced in Okinawa prefecture.

The history for which the turmeric is used as a medicine in Okinawa ( in a Ryukyu dynastic age), is old. The management cultivation was severely done as monopoly goods under the Ryukyu king in a Ryukyu dynastic age. The grown turmeric seems to have been sold to the Japanese whole country as a panacea through SATSUMA.

In photograph(Raw material):Turmeric ,Wild Turmeric, Zedoary
Product:UkonEX Capsule, UkonEX Sheet, UkonEX power, EnsekiUkon

2.Pharmacologic effect of turmeric

It is a liver function improvement and an effect of the hangover improvement that is known best by the pharmacologic effect of the turmeric.

Refer to data 1.: There is a functionality of the turmeric from the liver function improvement to the Alzheimer and the cancer control. The curcumin is strong anti-oxide.

Refer to data 2.:It was clarified that the curcumin was effective in the prevention of Alzheimer's disease by Prof. Yamada of the Kanazawa University graduate school.

In recent years, the liver function improvement, the controlling effect of cancer and the Alzheimer prevention effect are researched all over the world, and the result is obtained. The turmeric effective in the liver function improvement is discovered in a Ryukyu age of the dynasty, and has arrived at the present age. However, it is recognized only at the stomach and intestines medicine level though it arrives in Ayurveda and the Chinese medicine now.

The turmeric has a strong antioxidation effect which is that the anti-aging is effective. The effect of rejuvenation can be expected.

In addition, there is an action that improves the bile excretion.In the rat examination, bile 2-3 times the normal was admitted to be excreted by administering our product of turmeric extract.

Detoccs action of toxin, that is, effect of exhaust will rise because the liver excretes the toxin generated in the inside of the body as bile.

In addition, it is true known well that the decrease in the liver function is a cause of the skin roughness. On the other hand, if the liver function is normalized, the skin becomes glossy.That is, beautiful skin is effective.

The above-mentioned summary
1) Effect of liver function improvement and hangover controlling effect

2) Digestive medicine
3) Prevention of cancer and control of Alzheimer
4) Antioxidation effect and effect of anti-aging (effect of rejuvenation)
5) Bile excretion and effect of Detoccs
6) Effect of beautiful skin

3. The turmeric is dissolved in the cooking oil and the absorption factor of the curcumin has been increased by 350 times.

Though it is the turmeric with a wonderful like this pharmacologic effect, we are wrong for the intake of the active ingredient curcumin. It is hardly absorbed to the body that the turmeric is taken the shape of the powder or the tablet with water in common Okinawa, because the curcumin is not dissolved in water.

On the other hand, the absorption factor rises when the curcumin is dissolved in the cooking oil that blend is specially done by a special method. We, Microcell Co. Ltd. researched and developed the know-how of this manufacturing in advance of the world putting it for years.It is the turmeric extract that this explains in the product explanations.

If the absorption factor rises, the pharmacologic effect can be expected to rise that much.

The data 3) is a copy of the page of the chemical dictionary described for the curcumin of the turmeric is not dissolved in water.

4. Curcumin of 350 times absorption factor

Microcell Co. Ltd. have been doing a joint research on the turmeric extract turmeric extract containing the curcumin is dissolved in the cooking oil that blend is specially done by a special method with Organization of Okinawa Prefecture, Okinawa Industry Technology Center. Also, we did a joint research of absorption test on curcumin by using a rat with Sakamotobio Inc. The method of examining absorption oral administers of the following samples to the rat. These are; ① a sample that dissolved curcumin in water; ② a sample that melted curcumin in cooking oil; ③ a sample of turmeric extract in which curcumin is dissolved by a method of Microcel Co.Ltd.

Bile is gathered from the bile duct and the curcumin and the metabolic thing of the curcumin are measured by the time passage.

Figure 4 is a summary to figure as for acquired data through the above-mentioned absorption test.

Explanation of Figure 4

1)Graph of the left, C+water is an amount of total of curcumin and metabolic thing in bile when the above-mentioned sample ① was oral administered. It is not possible to measure it at all. Measurement lower bound of measuring instrument is 1.6 μg.

2)Graph of the middle, C+Oil is an amount of total of curcumin and metabolic thing in bile when the above-mentioned sample②was oral administered. Amount of measurement is 26 μg/ml.

3) Graph of the right, the sample ③ of the turmeric extract was administered. Amount of measurement is 571 μg/ml.

Calculation

Comparison between 1) and 3)
571÷1.6=350 times

That is, the absorption factor of the turmeric extract is a measurement result in which it is 350 times higher than the case to drink the powder of the turmeric.

5.Winning of highest award

The absorption factor of the turmeric extract that Microcell Co. Ltd. had developed was high and it was evaluated. And in 1999, the highest award was won from the Prefectural governor at an industrial festival of Okinawa Prefecture, Invention Device Exhibition.

Reference data5:It is an award certificate of "Highest award" in which I was given by the governor.

6. Raw material and process of manufacture

The elements of the turmeric such as Turmeric, Wild Turmeric and Zedoary collected from all over the world including Okinawa were measured in cooperation with the Okinawa industrial technology center. As for the raw material of the turmeric extract, those best turmeric are used as a medicine. Of course, we are confirming safety about foreign.

Table 6 is measurements of the curcumin of the turmeric extract.

Data 7 is an article that the Ministry of Health, Labour and Welfare in a Japanese country confirmed the safety of the curcumin.
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